Conditions · South Dakota

Does nausea and appetite loss qualify in South Dakota?

Yes. The South Dakota Medical Cannabis Program lists Severe nausea (except nausea associated with pregnancy) as a qualifying condition. A South Dakota-licensed provider still has to evaluate you and agree that cannabis is appropriate.

About nausea and appetite loss

Severe or persistent nausea and appetite loss can come from chemotherapy, HIV/AIDS, gastroparesis and other conditions, and can lead to dangerous weight loss.

Stronger evidence. There is conclusive evidence that oral cannabinoids treat chemotherapy-induced nausea and vomiting, and limited evidence that they increase appetite and reduce weight loss in HIV/AIDS.

Symptoms South Dakota patients most often hope to ease:

  • Nausea and vomiting during chemotherapy
  • Loss of appetite
  • Unwanted weight loss
  • Food aversions and changes in taste
  • Nausea that does not respond to standard medicines
Before you start. Heavy long-term cannabis use can rarely cause cannabinoid hyperemesis syndrome, which causes repeated severe vomiting. Cannabis is not recommended for nausea during pregnancy because THC can reach the baby.

Read more: medical marijuana for nausea and appetite loss.

How to get certified in South Dakota

  1. Confirm you have a debilitating medical condition listed in SDCL 34-20G-1.
  2. Visit a physician, PA or APRN for an in-person exam and get a written certification.
  3. Apply online at the Department of Health medical cannabis portal within 90 days of the certification date.
  4. Upload a copy of your unexpired photo ID and a 2x2 passport-style photo, and name up to two dispensaries and any caregiver.
  5. Pay $75, or $20 if your household income is under 130% of the federal poverty level, plus $20 if you want to grow at home.
  6. Wait for review, usually 2 to 4 days, then about 4 to 10 days for the card to arrive by mail.

South Dakota requires your first certification visit in person. Renewals can usually be done online.

Costs and timeline

  • State fee: $75 ($20 for households under 130% of the federal poverty level)
  • Card lasts: Up to 1 year (expiration set by the practitioner)
  • Processing: Applications typically reviewed within 2 to 4 days; mailed card arrives in about 4 to 10 days
  • Patient limit: 3 oz of cannabis plus product amounts set by Department rules
  • Home grow: 2 flowering and 2 non-flowering plants if the card allows cultivation ($20 add-on)
  • Recreational sales: Not legal
  • First visit online: No — in person first

See the full South Dakota cost breakdown and South Dakota program overview.

Other qualifying conditions in South Dakota

Nausea & appetite loss in nearby states

Frequently asked questions

Do I need medical records for nausea and appetite loss?

Helpful records include: records of the condition causing your nausea, such as a cancer treatment plan or GI diagnosis; a list of anti-nausea medicines you have tried and how well they worked; notes on weight changes, eating difficulties and how often you are sick. Many patients are still evaluated on their history alone, and your South Dakota provider will tell you if more is needed.

How long does certification take in South Dakota?

The provider visit takes about 15 minutes. Applications typically reviewed within 2 to 4 days; mailed card arrives in about 4 to 10 days.

Can I renew online in South Dakota?

In most cases, yes. Cards must be renewed at least yearly with a new practitioner certification and the full renewal fee. If your practitioner sees you for a follow-up within 60 days of the first certification and issues a second one, the fee is waived once per calendar year.

Sources

This guide is general information, not medical or legal advice. Laws change — confirm details with your state agency. State facts last checked October 7, 2026.

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