Conditions · South Dakota

Does cancer qualify for a medical card in South Dakota?

Yes. The South Dakota Medical Cannabis Program lists Cancer or its treatment, if associated with severe or chronic pain, nausea or severe vomiting, or cachexia or severe wasting as a qualifying condition. A South Dakota-licensed provider still has to evaluate you and agree that cannabis is appropriate.

About cancer

Cancer and its treatment — chemotherapy, radiation, surgery — can cause pain, nausea, vomiting, appetite loss and trouble sleeping.

Stronger evidence. The National Academies found conclusive evidence that oral cannabinoids prevent and treat chemotherapy-induced nausea and vomiting. There is not enough evidence that cannabis treats or cures cancer.

Symptoms South Dakota patients most often hope to ease:

  • Nausea and vomiting from chemotherapy
  • Loss of appetite and unwanted weight loss
  • Cancer-related pain
  • Burning or tingling nerve pain from chemotherapy
  • Trouble sleeping
Before you start. CBD can affect liver enzymes that process some chemotherapy and targeted drugs, so your oncology team must know about any cannabis you use. A few small studies have raised questions about whether cannabis use may affect how well immunotherapy works, which is worth discussing with your oncologist.

Read more: medical marijuana for cancer.

How to get certified in South Dakota

  1. Confirm you have a debilitating medical condition listed in SDCL 34-20G-1.
  2. Visit a physician, PA or APRN for an in-person exam and get a written certification.
  3. Apply online at the Department of Health medical cannabis portal within 90 days of the certification date.
  4. Upload a copy of your unexpired photo ID and a 2x2 passport-style photo, and name up to two dispensaries and any caregiver.
  5. Pay $75, or $20 if your household income is under 130% of the federal poverty level, plus $20 if you want to grow at home.
  6. Wait for review, usually 2 to 4 days, then about 4 to 10 days for the card to arrive by mail.

South Dakota requires your first certification visit in person. Renewals can usually be done online.

Costs and timeline

  • State fee: $75 ($20 for households under 130% of the federal poverty level)
  • Card lasts: Up to 1 year (expiration set by the practitioner)
  • Processing: Applications typically reviewed within 2 to 4 days; mailed card arrives in about 4 to 10 days
  • Patient limit: 3 oz of cannabis plus product amounts set by Department rules
  • Home grow: 2 flowering and 2 non-flowering plants if the card allows cultivation ($20 add-on)
  • Recreational sales: Not legal
  • First visit online: No — in person first

See the full South Dakota cost breakdown and South Dakota program overview.

Other qualifying conditions in South Dakota

Cancer in nearby states

Frequently asked questions

Do I need medical records for cancer?

Helpful records include: pathology or imaging reports confirming your cancer diagnosis; recent notes from your oncologist describing your stage and current treatment plan; a full list of medicines, including chemotherapy, anti-nausea drugs, pain medicines and blood thinners. Many patients are still evaluated on their history alone, and your South Dakota provider will tell you if more is needed.

How long does certification take in South Dakota?

The provider visit takes about 15 minutes. Applications typically reviewed within 2 to 4 days; mailed card arrives in about 4 to 10 days.

Can I renew online in South Dakota?

In most cases, yes. Cards must be renewed at least yearly with a new practitioner certification and the full renewal fee. If your practitioner sees you for a follow-up within 60 days of the first certification and issues a second one, the fee is waived once per calendar year.

Sources

This guide is general information, not medical or legal advice. Laws change — confirm details with your state agency. State facts last checked October 7, 2026.

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