Missouri qualifying conditions: the full official list

Yes. The constitution lets a physician certify any other chronic, debilitating or other medical condition in their professional judgment.

The official list

• ALS (Lou Gehrig's disease) — listed as “Any other chronic, debilitating or other medical condition in a physician's professional judgment (for example hepatitis C, ALS, inflammatory bowel disease, Crohn's disease, Huntington's disease, autism, neuropathies, sickle cell anemia, agitation of Alzheimer's disease, cachexia and wasting syndrom”
• Alzheimer's disease — listed as “Any other chronic, debilitating or other medical condition in a physician's professional judgment (for example hepatitis C, ALS, inflammatory bowel disease, Crohn's disease, Huntington's disease, autism, neuropathies, sickle cell anemia, agitation of Alzheimer's disease, cachexia and wasting syndrom”
• Autism spectrum disorder — listed as “Any other chronic, debilitating or other medical condition in a physician's professional judgment (for example hepatitis C, ALS, inflammatory bowel disease, Crohn's disease, Huntington's disease, autism, neuropathies, sickle cell anemia, agitation of Alzheimer's disease, cachexia and wasting syndrom”
• Cachexia & wasting syndrome — listed as “Any other chronic, debilitating or other medical condition in a physician's professional judgment (for example hepatitis C, ALS, inflammatory bowel disease, Crohn's disease, Huntington's disease, autism, neuropathies, sickle cell anemia, agitation of Alzheimer's disease, cachexia and wasting syndrom”
• Cancer
• Chronic pain — listed as “A chronic condition causing severe, persistent pain or persistent muscle spasms (including those linked to MS, seizures, Parkinson's disease and Tourette's syndrome)”
• Crohn's & IBD — listed as “Any other chronic, debilitating or other medical condition in a physician's professional judgment (for example hepatitis C, ALS, inflammatory bowel disease, Crohn's disease, Huntington's disease, autism, neuropathies, sickle cell anemia, agitation of Alzheimer's disease, cachexia and wasting syndrom”
• Epilepsy & seizures — listed as “Epilepsy”
• Glaucoma
• HIV/AIDS — listed as “HIV or AIDS”
• Hepatitis C — listed as “Any other chronic, debilitating or other medical condition in a physician's professional judgment (for example hepatitis C, ALS, inflammatory bowel disease, Crohn's disease, Huntington's disease, autism, neuropathies, sickle cell anemia, agitation of Alzheimer's disease, cachexia and wasting syndrom”
• Huntington's disease — listed as “Any other chronic, debilitating or other medical condition in a physician's professional judgment (for example hepatitis C, ALS, inflammatory bowel disease, Crohn's disease, Huntington's disease, autism, neuropathies, sickle cell anemia, agitation of Alzheimer's disease, cachexia and wasting syndrom”
• Migraines — listed as “Intractable migraines unresponsive to other treatment”
• Neuropathy (nerve pain) — listed as “Any other chronic, debilitating or other medical condition in a physician's professional judgment (for example hepatitis C, ALS, inflammatory bowel disease, Crohn's disease, Huntington's disease, autism, neuropathies, sickle cell anemia, agitation of Alzheimer's disease, cachexia and wasting syndrom”
• PTSD — listed as “Debilitating psychiatric disorders, including PTSD”
• Parkinson's disease — listed as “A chronic condition causing severe, persistent pain or persistent muscle spasms (including those linked to MS, seizures, Parkinson's disease and Tourette's syndrome)”
• Severe muscle spasms & spasticity — listed as “A chronic condition causing severe, persistent pain or persistent muscle spasms (including those linked to MS, seizures, Parkinson's disease and Tourette's syndrome)”
• Sickle cell disease — listed as “Any other chronic, debilitating or other medical condition in a physician's professional judgment (for example hepatitis C, ALS, inflammatory bowel disease, Crohn's disease, Huntington's disease, autism, neuropathies, sickle cell anemia, agitation of Alzheimer's disease, cachexia and wasting syndrom”
• Terminal illness & hospice — listed as “Any terminal illness”
• Tourette syndrome — listed as “A chronic condition causing severe, persistent pain or persistent muscle spasms (including those linked to MS, seizures, Parkinson's disease and Tourette's syndrome)”

Always confirm against the official Missouri list, which can change.

What to do next

1. See a Missouri physician or nurse practitioner for a certification (telemedicine is allowed if it meets the standard of care).
2. Submit your application within 30 days of the certification date through the DHSS online registry portal.
3. Upload a legible government-issued photo ID and a clear color photo of your face.
4. Pay the patient card fee, and add the cultivation authorization if you want to grow.
5. Wait for DHSS to decide, which it must do within 30 days.
6. Buy at licensed dispensaries with your patient ID card.

Sources

• DHSS - Cannabis Patient Services
• DHSS - Qualifying Medical Conditions
• DHSS - Patient & Consumer FAQs
• DHSS - Fee Schedule
• DHSS - Cultivation (Patient/Caregiver/Consumer)
• DHSS - General FAQs

This guide is general information, not medical or legal advice. Laws change — confirm details with your state agency. State facts last checked October 7, 2026.