Conditions · Missouri

Does epilepsy and seizures qualify in Missouri?

Yes. The Missouri Medical Marijuana Program lists Epilepsy as a qualifying condition. A Missouri-licensed provider still has to evaluate you and agree that cannabis is appropriate.

About epilepsy and seizures

Epilepsy is a brain disorder that causes repeated seizures. Some forms, like Dravet syndrome and Lennox-Gastaut syndrome, don't respond well to standard medications.

Stronger evidence. The FDA has approved a prescription CBD medicine (Epidiolex) for seizures linked to Lennox-Gastaut syndrome, Dravet syndrome and tuberous sclerosis complex, based on controlled trials.

Symptoms Missouri patients most often hope to ease:

  • Seizures that continue despite trying two or more medicines
  • Side effects such as tiredness and fogginess from seizure medicines
  • Poor sleep that can make seizures more likely
  • Anxiety about when the next seizure will happen
  • Mood and behavior changes linked to epilepsy
Before you start. Never stop or lower your seizure medicines on your own, because this can trigger severe or prolonged seizures. CBD can raise levels of clobazam and increase liver enzyme problems with valproate, and it can raise levels of everolimus used in tuberous sclerosis complex.

Read more: medical marijuana for epilepsy and seizures.

How to get certified in Missouri

  1. See a Missouri physician or nurse practitioner for a certification (telemedicine is allowed if it meets the standard of care).
  2. Submit your application within 30 days of the certification date through the DHSS online registry portal.
  3. Upload a legible government-issued photo ID and a clear color photo of your face.
  4. Pay the patient card fee, and add the cultivation authorization if you want to grow.
  5. Wait for DHSS to decide, which it must do within 30 days.
  6. Buy at licensed dispensaries with your patient ID card.

Missouri allows the evaluation by telehealth, so you can see a Missouri-licensed provider by video. Our evaluation starts at $79 and is charged only if you're approved.

Costs and timeline

  • State fee: $28.92 (July 2026-June 2027 fee schedule)
  • Card lasts: 3 years
  • Processing: DHSS has 30 days to process patient and caregiver applications
  • Patient limit: 60-day supply (12 oz of dried, unprocessed marijuana or equivalent); up to 90-day supply for patients with cultivation authorization, with the excess locked up
  • Home grow: With a cultivation authorization ($57.83): 6 flowering plants, 6 non-flowering plants over 14 inches and 6 under 14 inches per patient, in an enclosed, locked facility
  • Recreational sales: Legal for adults 21+
  • First visit online: Yes

See the full Missouri cost breakdown and Missouri program overview.

Other qualifying conditions in Missouri

See every qualifying condition in Missouri

Epilepsy & seizures in nearby states

Frequently asked questions

Do I need medical records for epilepsy and seizures?

Helpful records include: a neurologist's note confirming epilepsy and the seizure type or syndrome; EEG and MRI reports; a complete list of current and past seizure medicines, with doses and side effects. Many patients are still evaluated on their history alone, and your Missouri provider will tell you if more is needed.

How long does certification take in Missouri?

The provider visit takes about 15 minutes. DHSS has 30 days to process patient and caregiver applications.

Can I renew online in Missouri?

In most cases, yes. Patient cards last three years. Renew through the registry portal with a new physician or nurse practitioner certification before your card expires.

Sources

This guide is general information, not medical or legal advice. Laws change — confirm details with your state agency. State facts last checked October 7, 2026.

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