Migraines and medical marijuana in Missouri: do you qualify?
Yes. The Missouri Medical Marijuana Program lists Intractable migraines unresponsive to other treatment as a qualifying condition. A Missouri-licensed provider still has to evaluate you and agree that cannabis is appropriate.
About migraines
Limited evidence. Research is mostly observational. Survey studies report fewer and shorter migraines among patients who use cannabis, but there aren't yet large controlled trials.
Symptoms Missouri patients most often hope to ease:
- Throbbing headache pain during attacks
- Nausea and vomiting with attacks
- Frequent attacks that disrupt work and family life
- Trouble sleeping before or after an attack
- Neck and shoulder tension that comes with attacks
Read more: medical marijuana for migraines.
How to get certified in Missouri
- See a Missouri physician or nurse practitioner for a certification (telemedicine is allowed if it meets the standard of care).
- Submit your application within 30 days of the certification date through the DHSS online registry portal.
- Upload a legible government-issued photo ID and a clear color photo of your face.
- Pay the patient card fee, and add the cultivation authorization if you want to grow.
- Wait for DHSS to decide, which it must do within 30 days.
- Buy at licensed dispensaries with your patient ID card.
Missouri allows the evaluation by telehealth, so you can see a Missouri-licensed provider by video. Our evaluation starts at $79 and is charged only if you're approved.
Costs and timeline
- State fee: $28.92 (July 2026-June 2027 fee schedule)
- Card lasts: 3 years
- Processing: DHSS has 30 days to process patient and caregiver applications
- Patient limit: 60-day supply (12 oz of dried, unprocessed marijuana or equivalent); up to 90-day supply for patients with cultivation authorization, with the excess locked up
- Home grow: With a cultivation authorization ($57.83): 6 flowering plants, 6 non-flowering plants over 14 inches and 6 under 14 inches per patient, in an enclosed, locked facility
- Recreational sales: Legal for adults 21+
- First visit online: Yes
See the full Missouri cost breakdown and Missouri program overview.
Other qualifying conditions in Missouri
- ALS (Lou Gehrig's disease)
- Alzheimer's disease
- Autism spectrum disorder
- Cachexia & wasting syndrome
- Cancer
- Chronic pain
- Crohn's & IBD
- Epilepsy & seizures
- Glaucoma
- HIV/AIDS
- Hepatitis C
- Huntington's disease
- Neuropathy (nerve pain)
- PTSD
See every qualifying condition in Missouri
Migraines in nearby states
- Migraines in Illinois
- Migraines in Kentucky
- Migraines in Arkansas
Frequently asked questions
Do I need medical records for migraines?
How long does certification take in Missouri?
Can I renew online in Missouri?
Sources
- DHSS - Cannabis Patient Services
- DHSS - Qualifying Medical Conditions
- DHSS - Patient & Consumer FAQs
- DHSS - Fee Schedule
- DHSS - Cultivation (Patient/Caregiver/Consumer)
- DHSS - General FAQs
- National Academies — The Health Effects of Cannabis and Cannabinoids (2017)
This guide is general information, not medical or legal advice. Laws change — confirm details with your state agency. State facts last checked October 7, 2026.