Conditions · Mississippi

Does ALS (Lou Gehrig's disease) qualify in Mississippi?

Yes. The Mississippi Medical Cannabis Program lists Amyotrophic lateral sclerosis (ALS) as a qualifying condition. A Mississippi-licensed provider still has to evaluate you and agree that cannabis is appropriate.

About ALS (Lou Gehrig's disease)

A progressive disease that destroys the nerve cells controlling muscles, causing weakness, cramps and trouble swallowing.

Not enough research. Research is limited to small studies. Patients mainly use cannabis for cramps, spasticity, appetite, drooling and sleep.

Symptoms Mississippi patients most often hope to ease:

  • Painful muscle cramps and twitching
  • Stiffness and spasticity in the arms and legs
  • Loss of appetite and unwanted weight loss
  • Trouble falling or staying asleep
  • Excess saliva and drooling
Before you start. Sedating effects can add to breathing weakness, so tell your doctor about any breathing problems, sleep apnea or use of a breathing machine. Smoking or vaping can irritate the airways and is generally avoided when lung function is reduced.

Read more: medical marijuana for ALS (Lou Gehrig's disease).

How to get certified in Mississippi

  1. Find a practitioner registered with MSDH (MD, DO, NP, PA or optometrist) and have an in-person evaluation.
  2. The practitioner submits your written certification electronically to MSDH.
  3. Create an account on the MSDH licensing portal and complete the patient application.
  4. Pay the $25 card fee ($15 for Medicaid; waived for qualifying disabled veterans and first responders).
  5. MSDH reviews the application within about 10 days, and your card is available to print within 5 days of approval.
  6. Buy at licensed dispensaries within your MMCEU limits.

Mississippi requires your first certification visit in person. Renewals can usually be done online.

Costs and timeline

  • State fee: $25 ($15 for Medicaid participants; waived for disabled veterans and first responders with documentation)
  • Card lasts: 1 year (unless the practitioner sets a shorter term)
  • Processing: 10-day review; card available within 5 days of approval
  • Patient limit: 28 MMCEUs for residents; 14 MMCEUs for non-residents
  • Home grow: Not allowed
  • Recreational sales: Not legal
  • First visit online: No — in person first

See the full Mississippi cost breakdown and Mississippi program overview.

Other qualifying conditions in Mississippi

See every qualifying condition in Mississippi

ALS (Lou Gehrig's disease) in nearby states

Frequently asked questions

Do I need medical records for ALS (Lou Gehrig's disease)?

Helpful records include: a diagnosis letter or clinic notes from your neurologist or ALS clinic confirming ALS; a current list of all your medicines, including riluzole, edaravone, muscle relaxants and sleep aids; recent notes on breathing tests and swallowing assessments, if you have them. Many patients are still evaluated on their history alone, and your Mississippi provider will tell you if more is needed.

How long does certification take in Mississippi?

The provider visit takes about 15 minutes. 10-day review; card available within 5 days of approval.

Can I renew online in Mississippi?

In most cases, yes. Certification and the card are good for one year. Renew annually through the portal with a new certification, which can be done by telehealth if your practitioner has already seen you in person. The fee is the same as for a new card.

Sources

This guide is general information, not medical or legal advice. Laws change — confirm details with your state agency. State facts last checked October 7, 2026.

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